Bisphosphonates and OA — is there a bone and joint connection?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://www.nature.com/articles/nrrheum.2018.18.pdf
Reference8 articles.
1. Vaysbrot, E. E. et al. Are bisphosphonates efficacious in knee osteoarthritis? A meta-analysis of randomized controlled trials. Osteoarthritis Cartilage https://doi.org/10.1016/j.joca.2017.11.013 (2017).
2. Spector, T. D. et al. Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISH randomized, controlled trial. Arthritis Res. Ther. 7, R625–R633 (2004).
3. Bingham, C. O. et al. Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee. Arthritis Rheum. 54, 3494–3507 (2006).
4. Hunter, D. J. et al. Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis. Arthritis Rheum. 54, 1529–1535 (2006).
5. Laslett, L. L. et al. Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomized controlled trial. Ann. Rheum. Dis. 71, 1322–1328 (2012).
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