Age-related OA—a concept emerging from infancy?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://www.nature.com/articles/nrrheum.2011.206.pdf
Reference10 articles.
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2. Aigner, T., Söder, S., Gebhard, P. M., McAlinden, A. & Haag, J. Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis—structure, chaos and senescence. Nat. Clin. Pract. Rheumatol. 3, 391–399 (2007).
3. Martin, J. A., Ellerbroek, S. M. & Buckwalter, J. A. Age-related decline in chondrocyte response to insulin-like growth factor-I: the role of growth factor binding proteins. J. Orthop. Res. 15, 491–498 (1997).
4. Loeser, R. F. Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix. Osteoarthritis Cartilage 17, 971–979 (2009).
5. Loeser, R. F. et al. Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice. Arthritis Rheum. http:dx.doi.org/10.1002/art.33388
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