Is OA a mechanical or systemic disease?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://www.nature.com/articles/nrrheum.2014.114.pdf
Reference10 articles.
1. Visser, A. W. et al. The relative contribution of mechanical stress and systemic processes in different types of osteoarthritis: the NEO study. Ann. Rheum Dis. http://dx.doi.org/10.1136/annrheumdis-2013-205012 (2014).
2. Jones, G., Ding, C., Scott, F., Glisson, M. & Cicuttini, F. Early radiographic osteoarthritis is associated with substantial changes in cartilage volume and tibial bone surface area in both males and females. Osteoarthritis Cartilage 12, 169–174 (2004).
3. Cicuttini, F. M., Jones, G., Forbes, A. & Wluka, A. E. Rate of cartilage loss at two years predicts subsequent total knee arthroplasty: a prospective study. Ann. Rheum. Dis. 63, 1124–1127 (2004).
4. Stannus, O. et al. Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults. Osteoarthritis Cartilage 18, 1441–1447 (2010).
5. Jin, X. et al. Circulating C reactive protein in osteoarthritis: a systematic review and meta-analysis. Ann. Rheum. Dis. http://dx.doi.org/10.1136/annrheumdis-2013-204494 (2013).
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