New tools to tackle inflammatory arthritis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://www.nature.com/articles/nrrheum.2015.180.pdf
Reference10 articles.
1. Frenzel, E. et al. Acute-phase protein α1-antitrypsin — a novel regulator of angiopoietin-like protein 4 transcription and secretion. J. Immunol. 192, 5354–5362 (2014).
2. Joosten, L. A. et al. Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. Arthritis Rheum. 62, 3237–3248 (2010).
3. Joosten, L. A. et al. α-1-anti-trypsin–Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra. Ann. Rheum. Dis. http://dx.doi.org/10.1136/annrheumdis-2014-206966 (2015).
4. Abbate, A. et al. Effects of Prolastin C (plasma-derived α-1 antitrypsin) on the acute inflammatory response in patients with ST-segment elevation myocardial infarction (from the VCU-α 1-RT pilot study). Am. J. Cardiol. 115, 8–12 (2015).
5. Crisan, T. O. et al. Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra. Ann. Rheum. Dis. http://dx.doi.org/10.1136/annrheumdis-2014-206564 (2015).
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