Impact of CFTR Modulation on Intestinal pH, Motility, and Clinical Outcomes in Patients With Cystic Fibrosis and the G551D Mutation

Author:

Gelfond Daniel,Heltshe Sonya,Ma Changxing,Rowe Steven M,Frederick Carla,Uluer Ahmet,Sicilian Leonard,Konstan Michael,Tullis Elizabeth,Roach Christine R N,Griffin Katherine,Joseloff Elizabeth,Borowitz Drucy

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Gastroenterology

Reference25 articles.

1. CFTR functions as a bicarbonate channel in pancreatic duct cells.;Ishiguro;J Gen Physiol,2009

2. Pancreatic bicarbonate secretion involves two proton pumps.;Novak;J Biol Chem,2011

3. Review article: duodenal bicarbonatemucosal protection, luminal chemosensing and acid-base balance.;Kaunitz;Aliment Pharmacol Ther,2006

4. Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis.;Quinton;Lancet,2008

5. Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype.;Gustafsson;J Exp Med,2012

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