Role of brainstem thyrotropin-releasing hormone-triggered sympathetic overactivation in cardiovascular mortality in type 2 diabetic Goto

Role of brainstem thyrotropin-releasing hormone-triggered sympathetic overactivation in cardiovascular mortality in type 2 diabetic Goto–Kakizaki rats

Published:2011-09-08 Issue:2 Volume:35 Page:157-165
ISSN:0916-9636
Container-title:Hypertension Research
language:en
Short-container-title:Hypertens Res

Author:

Yang Hong,Nyby Michael D,Ao Yan,Chen Ai,Adelson David W,Smutko Victoria,Wijesuriya Janake,Go Vay Liang W,Tuck Michael L

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Physiology,Internal Medicine

Link

http://www.nature.com/articles/hr2011154.pdf

Reference53 articles.

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3. Malpas SC . Sympathetic nervous system overactivity and its role in the development of cardiovascular disease. Physiol Rev 2010; 90: 513–557.

4. Palatini P, Julius S . The role of cardiac autonomic function in hypertension and cardiovascular disease. Curr Hypertens Rep 2009; 11: 199–205.

5. Taegtmeyer H, Golfman L, Sharma S, Razeghi P, van AM . Linking gene expression to function: metabolic flexibility in the normal and diseased heart. Ann NY Acad Sci 2004; 1015: 202–213.

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1. The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?;Frontiers in Pharmacology;2020-05-08

2. Voltage dependence of the Ca2+ transient in endocardial and epicardial myocytes from the left ventricle of Goto–Kakizaki type 2 diabetic rats;Molecular and Cellular Biochemistry;2018-01-09

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4. Food-intake dysregulation in type 2 diabetic Goto-Kakizaki rats: Hypothesized role of dysfunctional brainstem thyrotropin-releasing hormone and impaired vagal output;Neuroscience;2013-09