Molecular mechanisms of dietary restriction promoting health and longevity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
https://www.nature.com/articles/s41580-021-00411-4.pdf
Reference308 articles.
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2. Kenyon, C. J. The genetics of ageing. Nature 464, 504–512 (2010).
3. Speakman, J. R. & Mitchell, S. E. Caloric restriction. Mol. Asp. Med. 32, 159–221 (2011).
4. Liao, C. Y., Rikke, B. A., Johnson, T. E., Diaz, V. & Nelson, J. F. Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell 9, 92–95 (2010).
5. Mitchell, S. J. et al. Effects of sex, strain, and energy intake on hallmarks of aging in mice. Cell Metab. 23, 1093–1112 (2016). This study by Mitchell et al. shows that sex, genetic background and the degree of restriction determine the impact of DR on the lifespan of mice.
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