JNK is required for effector T-cell function but not for T-cell activation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/35011091.pdf
Reference16 articles.
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2. Li,B., Tournier,C., Davis,R. J. & Flavell,R. A. Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J. 18, 420–432 (1999).
3. Su,B. et al. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77, 727– 736 (1994).
4. Matsuda,S., Moriguchi,T., Koyasu,S. & Nishida,E. T-Lymphocyte activation signals for Interleukin-2 production involve activation of MKK6-p38 and MKK7-SAPK/JNK signaling pathways sensitive to cyclosporin A. J. Biol. Chem. 273, 12378–123782 (1998 ).
5. Dong,C. et al. Defective T-cell differentiation in the absence of Jnk1. Science 282, 2092–2095 ( 1998).
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