A new frontier in FGF21 biology
Author:
Publisher
Springer Science and Business Media LLC
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
http://www.nature.com/articles/nrendo.2016.206.pdf
Reference10 articles.
1. Markan, K. R. & Potthoff, M. J. Metabolic fibroblast growth factors (FGFs): mediators of energy homeostasis. Semin. Cell Dev. Biol. 53, 85–93 (2016).
2. Talukdar, S. et al. A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects. Cell Metab. 23, 427–440 (2016).
3. Gaich, G. et al. The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes. Cell Metab. 18, 333–340 (2013).
4. von Holstein-Rathlou, S. et al. FGF21 mediates endocrine control of simple sugar intake and sweet taste preference by the liver. Cell Metab. 23, 335–343 (2016).
5. Chu, A. Y. et al. Novel locus including FGF21 is associated with dietary macronutrient intake. Hum. Mol. Genet. 22, 1895–1902 (2013).
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