Endpoints and estimands: understanding trials of weight-loss drugs

Author:

Adler Amanda I.ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference11 articles.

1. Patel, M. R., Donahue, M., Wilson, P. W. & Califf, R. M. Am. Heart J. 151, 633–642 (2006).

2. US Department of Health and Human Services Food and Drug Administration. https://www.fda.gov/media/71252/download (2007).

3. Garvey, W. et al. Nat. Med. https://doi.org/10.1038/s41591-022-02026-4 (2022).

4. US Department of Health and Human Services Food and Drug Administration. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/multiple-endpoints-clinical-trials-guidance-industry (2017).

5. European Medicines Agency Committee for Medicinal Products for Human Use. https://www.ema.europa.eu/en/documents/scientific-guideline/ich-e9-r1-addendum-estimands-sensitivity-analysis-clinical-trials-guideline-statistical-principles_en.pdf (2020).

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