Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
https://www.nature.com/articles/s41591-021-01645-7.pdf
Reference79 articles.
1. Sneddon, J. B. et al. Stem cell therapies for treating diabetes: progress and remaining challenges. Cell Stem Cell 22, 810–823 (2018).
2. Nair, G. G., Tzanakakis, E. S. & Hebrok, M. Emerging routes to the generation of functional β-cells for diabetes mellitus cell therapy. Nat. Rev. Endocrinol. 16, 506–518 (2020).
3. Harding, J. D. Nonhuman primates and translational research: progress, opportunities, and challenges. ILAR J. 58, 141–150 (2017).
4. Katsarou, A. et al. Type 1 diabetes mellitus. Nat. Rev. Dis. Prim. 3, 17016 (2017).
5. Vantyghem, M. C., de Koning, E. J. P., Pattou, F. & Rickels, M. R. Advances in β-cell replacement therapy for the treatment of type 1 diabetes. Lancet 394, 1274–1285 (2019).
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