Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells-Reference-Cited by-同舟云学术

Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells

Published:2018-05-28 Issue:6 Volume:24 Page:739-748
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Norelli Margherita,Camisa Barbara,Barbiera Giulia,Falcone Laura,Purevdorj Ayurzana,Genua Marco,Sanvito Francesca,Ponzoni Maurilio,Doglioni Claudio^ORCID,Cristofori Patrizia,Traversari Catia,Bordignon Claudio,Ciceri Fabio,Ostuni Renato,Bonini Chiara,Casucci Monica,Bondanza Attilio

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/s41591-018-0036-4.pdf

Reference42 articles.

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3. Kochenderfer, J. N. et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119, 2709–2720 (2012).

4. Porter, D. L., Levine, B. L., Kalos, M., Bagg, A. & June, C. H. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N. Engl. J. Med. 365, 725–733 (2011).

5. Grupp, S. A. et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N. Engl. J. Med. 368, 1509–1518 (2013).

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