Integrative multi-omics profiling in human decedents receiving pig heart xenografts
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Published:2024-05
Issue:5
Volume:30
Page:1448-1460
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ISSN:1078-8956
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Container-title:Nature Medicine
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language:en
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Short-container-title:Nat Med
Author:
Schmauch Eloi, Piening BrianORCID, Mohebnasab MaedehORCID, Xia BoORCID, Zhu Chenchen, Stern JeffreyORCID, Zhang WeiminORCID, Dowdell Alexa K.ORCID, Kim Jacqueline I.ORCID, Andrijevic DavidORCID, Khalil KarenORCID, Jaffe Ian S.ORCID, Loza Bao-Li, Gragert Loren, Camellato Brendan R., Oliveira Michelli F., O’Brien Darragh P.ORCID, Chen Han M.ORCID, Weldon Elaina, Gao Hui, Gandla Divya, Chang AndrewORCID, Bhatt Riyana, Gao Sarah, Lin XiangpingORCID, Reddy Kriyana P., Kagermazova Larisa, Habara Alawi H.ORCID, Widawsky Sophie, Liang Feng-XiaORCID, Sall Joseph, Loupy Alexandre, Heguy AdrianaORCID, Taylor Sarah E. B., Zhu Yinan, Michael BasilORCID, Jiang Lihua, Jian Ruiqi, Chong Anita S., Fairchild Robert L., Linna-Kuosmanen SuviORCID, Kaikkonen Minna U.ORCID, Tatapudi Vasishta, Lorber Marc, Ayares David, Mangiola Massimo, Narula Navneet, Moazami NaderORCID, Pass Harvey, Herati Ramin S.ORCID, Griesemer AdamORCID, Kellis ManolisORCID, Snyder Michael P.ORCID, Montgomery Robert A., Boeke Jef D.ORCID, Keating Brendan J.ORCID
Funder
U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases Laura and Isaac Perlmutter Cancer Center Support Grant Orionin Tutkimussäätiö Yrjö Jahnssonin Säätiö Suomalainen Tiedeakatemia Aarne Koskelon Säätiö Itä-Suomen Yliopisto Antti and Tyyne Soininen Foundation
Publisher
Springer Science and Business Media LLC
Reference62 articles.
1. Cooper, D. K. C. & Pierson, R. N. Milestones on the path to clinical pig organ xenotransplantation. Am. J. Transpl. 23, 326–335 (2023). 2. Wolbrom, D. H., Kim, J. I. & Griesemer, A. The road to xenotransplantation. Curr. Opin. Organ Transpl. 28, 65–70 (2023). 3. Ekser, B., Rigotti, P., Gridelli, B. & Cooper, D. K. C. Xenotransplantation of solid organs in the pig-to-primate model. Transpl. Immunol. 21, 87–92 (2009). 4. Pintore, L. et al. Clinicopathological findings in non-human primate recipients of porcine renal xenografts: quantitative and qualitative evaluation of proteinuria. Xenotransplantation 20, 449–457 (2013). 5. Mohiuddin, M. M. et al. Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report. Lancet 402, 397–410 (2023).
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