A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma-Reference-Cited by-同舟云学术

A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma

Published:2019-02-25 Issue:3 Volume:25 Page:454-461
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Huang Alexander C.^ORCID,Orlowski Robert J.,Xu Xiaowei,Mick Rosemarie,George Sangeeth M.,Yan Patrick K.^ORCID,Manne Sasikanth,Kraya Adam A.,Wubbenhorst Bradley,Dorfman Liza,D’Andrea Kurt,Wenz Brandon M.,Liu Shujing,Chilukuri Lakshmi,Kozlov Andrew,Carberry Mary,Giles Lydia,Kier Melanie W.,Quagliarello Felix,McGettigan Suzanne,Kreider Kristin,Annamalai Lakshmanan,Zhao Qing,Mogg Robin,Xu Wei,Blumenschein Wendy M.,Yearley Jennifer H.,Linette Gerald P.,Amaravadi Ravi K.,Schuchter Lynn M.,Herati Ramin S.,Bengsch Bertram,Nathanson Katherine L.,Farwell Michael D.,Karakousis Giorgos C.,Wherry E. John^ORCID,Mitchell Tara C.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/s41591-019-0357-y.pdf

Reference42 articles.

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3. Huang, A. C. et al. T-cell invigoration to tumour burden ratio associated with anti-PD-1 response. Nature 545, 60–65 (2017).

4. Kamphorst, A. O. et al. Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients. Proc. Natl Acad. Sci. USA 114, 4993–4998 (2017).

5. Hellmann, M. D. et al. Pathological response after neoadjuvant chemotherapy in resectable non-small-cell lung cancers: proposal for the use of major pathological response as a surrogate endpoint. Lancet Oncol. 15, e42–e50 (2014).

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