Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/s41591-018-0022-x.pdf
Reference47 articles.
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4. Dulak, A. M. et al. Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis. Cancer Res. 72, 4383–4393 (2012).
5. Chen, Y. et al. Identification of druggable cancer driver genes amplified across TCGA datasets. PloS ONE 9, e98293 (2014).
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