Detailed mapping of chromatin accessibility and transcriptome of the healthy breast

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Springer Science and Business Media LLC

Reference5 articles.

1. Mouabbi, J. A. et al. Invasive lobular carcinoma: an understudied emergent subtype of breast cancer. Breast Cancer Res. Treat. 193, 253–264 (2022). This review article describes clinical features of lobular carcinoma of the breast.

2. Degnim, A. C. et al. Histologic findings in normal breast tissues: comparison to reduction mammaplasty and benign breast disease tissues. Breast Cancer Res. Treat. 133, 169–177 (2012). This article compared breast tissues donated by healthy women to our bank with that of reduction mammoplasty and benign breast disease samples for histological abnormalities.

3. Bhat-Nakshatri, P. et al. A single-cell atlas of the healthy breast tissues reveals clinically relevant clusters of breast epithelial cells. Cell Rep. Med. 2, 100219 (2021). To our knowledge, this is the first single-cell atlas using breast tissue biopsy samples from healthy donors and described distinct subtypes of estrogen-receptor-positive cells.

4. Wu, S. Z. et al. A single-cell and spatially resolved atlas of human breast cancers. Nat. Genet. 53, 1334–1347 (2021). Using single-cell techniques, this study described intrinsic subtype classification and outlined cellular architecture of breast cancer.

5. Fachal, L. et al. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. Nat. Genet. 52, 56–73 (2020). This report mapped potentially causal risk variants to active gene regulatory regions and transcription factor binding sites using publicly available data of breast cancer cell lines.

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