Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
-
Published:2022-01-13
Issue:2
Volume:28
Page:333-344
-
ISSN:1078-8956
-
Container-title:Nature Medicine
-
language:en
-
Short-container-title:Nat Med
Author:
Theruvath Johanna, Menard Marie, Smith Benjamin A. H.ORCID, Linde Miles H.ORCID, Coles Garry L., Dalton Guillermo Nicolas, Wu Wei, Kiru Louise, Delaidelli Alberto, Sotillo Elena, Silberstein John L., Geraghty Anna C., Banuelos Allison, Radosevich Molly Thomas, Dhingra Shaurya, Heitzeneder Sabine, Tousley Aidan, Lattin John, Xu Peng, Huang Jing, Nasholm Nicole, He Andy, Kuo Tracy C.ORCID, Sangalang Emma R. B., Pons Jaume, Barkal Amira, Brewer Rachel E., Marjon Kristopher D., Vilches-Moure Jose G., Marshall Payton L., Fernandes Ricardo, Monje MichelleORCID, Cochran Jennifer R.ORCID, Sorensen Poul H.ORCID, Daldrup-Link Heike E.ORCID, Weissman Irving L.ORCID, Sage JulienORCID, Majeti RavindraORCID, Bertozzi Carolyn R.ORCID, Weiss William A.ORCID, Mackall Crystal L.ORCID, Majzner Robbie G.ORCID
Funder
Alex’s Lemonade Stand Foundation for Childhood Cancer Deutsche Krebshilfe U.S. Department of Health & Human Services | NIH | National Cancer Institute
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference67 articles.
1. Schulz, G. et al. Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients. Cancer Res. 44, 5914–5920 (1984). 2. Long, A. H. et al. Reduction of MDSCs with all-trans retinoic acid improves CAR therapy efficacy for sarcomas. Cancer Immunol. Res. 4, 869–880 (2016). 3. Dobrenkov, K., Ostrovnaya, I., Gu, J., Cheung, I. Y. & Cheung, N. K. Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents, and young adults. Pediatr. Blood Cancer 63, 1780–1785 (2016). 4. Mount, C. W. et al. Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas. Nat. Med. 24, 572–579 (2018). 5. Cheresh, D. A., Rosenberg, J., Mujoo, K., Hirschowitz, L. & Reisfeld, R. A. Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis. Cancer Res. 46, 5112–5118 (1986).
Cited by
138 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|