CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption-Reference-Cited by-同舟云学术

CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption

Published:2020-03-16 Issue:4 Volume:26 Page:519-528
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Harper Justin^ORCID,Gordon Shari,Chan Chi Ngai,Wang Hong,Lindemuth Emily,Galardi Cristin,Falcinelli Shane D.^ORCID,Raines Samuel L. M.,Read Jenna L.,Nguyen Kevin,McGary Colleen S,Nekorchuk Michael,Busman-Sahay Kathleen,Schawalder James,King Colin,Pino Maria,Micci Luca,Cervasi Barbara,Jean Sherrie,Sanderson Andrew,Johns Brian,Koblansky A. Alicia,Amrine-Madsen Heather,Lifson Jeffrey,Margolis David M.^ORCID,Silvestri Guido,Bar Katharine J.,Favre David^ORCID,Estes Jacob D.,Paiardini Mirko^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/s41591-020-0782-y.pdf

Reference54 articles.

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2. Banga, R. et al. PD-1+ and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals. Nat. Med. 22, 754–761 (2016).

3. Fromentin, R. et al. CD4+ T cells expressing PD-1, TIGIT and LAG-3 contribute to HIV persistence during ART. PLoS Pathog. 12, e1005761 (2016).

4. Perez, V. L. et al. Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity 6, 411–417 (1997).

5. Fife, B. T. & Bluestone, J. A. Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. Immunol. Rev. 224, 166–182 (2008).

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