Overcoming myelodysplastic syndrome progression after frontline therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
https://www.nature.com/articles/s41591-022-01716-3.pdf
Reference5 articles.
1. Shastri, A., Will, B., Steidl, U. & Verma, A. Stem and progenitor cell alterations in myelodysplastic syndromes. Blood 129, 1586–1594 (2017). A review article that describes the alterations in stem and progenitor cells in MDSs.
2. Sperling, A. S., Gibson, C. J. & Ebert, B. L. The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia. Nat. Rev. Cancer 17, 5–19 (2017). A review article that summarizes the genetic aberrations at various stages of MDSs.
3. Garcia-Manero, G. Demethylating agents in myeloid malignancies. Curr. Opin. Oncol. 20, 705–710 (2008). A review article that summarizes the initial discovery that HMA therapy can improve the survival of patients with MDSs.
4. Kadia, T. M., Jabbour, E. & Kantarjian, H. Failure of hypomethylating agent-based therapy in myelodysplastic syndromes. Semin. Oncol. 38, 682–692 (2011). A paper that reports the survival of patients with MDSs after HMA therapy failure.
5. Chen, J. et al. Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level. Nat. Med. 25, 103–110 (2019). A paper reporting that MDS progression arises from the HSC compartment.
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