Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice-Reference-Cited by-同舟云学术

Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice

Published:2023-02 Issue:2 Volume:29 Page:401-411
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Chai Andreas C.^ORCID,Cui Miao,Chemello Francesco^ORCID,Li Hui^ORCID,Chen Kenian,Tan Wei,Atmanli Ayhan,McAnally John R.,Zhang Yu^ORCID,Xu Lin^ORCID,Liu Ning,Bassel-Duby Rhonda^ORCID,Olson Eric N.^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute

U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development

Foundation Leducq Transatlantic Networks of Excellence in Cardiovascular Research Robert A. Welch Foundation

American Heart Association

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

https://www.nature.com/articles/s41591-022-02176-5.pdf

Reference65 articles.

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2. Semsarian, C., Ingles, J., Maron, M. S. & Maron, B. J. New perspectives on the prevalence of hypertrophic cardiomyopathy. J. Am. Coll. Cardiol. 65, 1249–1254 (2015).

3. Trivedi, D. V., Adhikari, A. S., Sarkar, S. S., Ruppel, K. M. & Spudich, J. A. Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light. Biophys. Rev. 10, 27–48 (2018).

4. Geisterfer-Lowrance, A. A. et al. A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation. Cell 62, 999–1006 (1990).

5. Tyska, M. J. et al. Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy. Circ. Res. 86, 737–744 (2000).

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