Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss-Reference-Cited by-同舟云学术

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

Published:2019-07 Issue:7 Volume:25 Page:1123-1130
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

György Bence^ORCID,Nist-Lund Carl,Pan Bifeng^ORCID,Asai Yukako,Karavitaki K. Domenica,Kleinstiver Benjamin P.^ORCID,Garcia Sara P.,Zaborowski Mikołaj P.,Solanes Paola,Spataro Sofia,Schneider Bernard L.^ORCID,Joung J. Keith^ORCID,Géléoc Gwenaëlle S. G.,Holt Jeffrey R.^ORCID,Corey David P.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/s41591-019-0500-9.pdf

Reference30 articles.

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2. Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A. & Liu, D. R. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature 533, 420–424 (2016).

3. Tsai, S. Q. et al. GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases. Nat. Biotechnol. 33, 187–198 (2015).

4. Ran, F. A. et al. Genome engineering using the CRISPR-Cas9 system. Nat. Protoc. 8, 2281–2308 (2013).

5. Vreugde, S. et al. Beethoven, a mouse model for dominant, progressive hearing loss DFNA36. Nat. Genet. 30, 257–258 (2002).

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