Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial
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Published:2021-09-23
Issue:10
Volume:27
Page:1818-1824
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ISSN:1078-8956
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Container-title:Nature Medicine
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language:en
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Short-container-title:Nat Med
Author:
Ho Carolyn Y.ORCID, Day Sharlene M., Axelsson Anna, Russell Mark W., Zahka Kenneth, Lever Harry M., Pereira Alexandre C., Colan Steven D.ORCID, Margossian Renee, Murphy Anne M., Canter Charles, Bach Richard G., Wheeler Matthew T.ORCID, Rossano Joseph W., Owens Anjali T., Bundgaard Henning, Benson Lee, Mestroni Luisa, Taylor Matthew R. G., Patel Amit R., Wilmot Ivan, Thrush Philip, Vargas Jose D., Soslow Jonathan H., Becker Jason R., Seidman Christine E.ORCID, Lakdawala Neal K.ORCID, Cirino Allison L., Krieger Jose E., Sacilotto Luciana, Arteaga Edmundo, Antunes Murilo O., Hall E. Kevin, Choudhury Lubna, Pahl Elfriede, Lin Kimberly Y., Lewis Gregory D., Desai Akshay S., Burns Kristin M., McMurray John J. V.ORCID, MacRae Calum A., Solomon Scott D., Orav E. John, Braunwald Eugene,
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference23 articles.
1. Writing Committee M. et al. 2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 142, e558–e631 (2020). 2. Seidman, C. E. & Seidman, J. G. Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history. Circ. Res. 108, 743–750 (2011). 3. Ho, C. Y. et al. Genotype and lifetime burden of disease in hypertrophic cardiomyopathy: insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe). Circulation 138, 1387–1398 (2018). 4. Kim, J. B. et al. Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy. Science 316, 1481–1484 (2007). 5. Lopez, B., Gonzalez, A. & Diez, J. Circulating biomarkers of collagen metabolism in cardiac diseases. Circulation 121, 1645–1654 (2010).
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