Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer-Reference-Cited by-同舟云学术

Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

Published:2018-06-11 Issue:7 Volume:24 Page:1047-1057
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Lissanu Deribe Yonathan,Sun Yuting,Terranova Christopher,Khan Fatima,Martinez-Ledesma Juan,Gay Jason,Gao Guang,Mullinax Robert A.,Khor Tin,Feng Ningping,Lin Yu-Hsi,Wu Chia-Chin,Reyes Claudia,Peng Qian,Robinson Frederick,Inoue Akira,Kochat Veena,Liu Chang-Gong,Asara John M.,Moran Cesar,Muller Florian,Wang Jing,Fang Bingliang,Papadimitrakopoulou Vali,Wistuba Ignacio I.,Rai Kunal,Marszalek Joseph,Futreal P. Andrew

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/s41591-018-0019-5.pdf

Reference61 articles.

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2. Kadoch, C. et al. Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nat. Genet. 45, 592–601 (2013).

3. Wilson, B. G. & Roberts, C. W. SWI/SNF nucleosome remodellers and cancer. Nat. Rev. Cancer 11, 481–492 (2011).

4. Wilson, B. G. et al. Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer Cell 18, 316–328 (2010).

5. Stanton, B.Z. et al. Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin. Nat. Genet. 49, 282–288 (2016).

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