Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas
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Published:2020-01
Issue:1
Volume:26
Page:110-117
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ISSN:1078-8956
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Container-title:Nature Medicine
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language:en
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Short-container-title:Nat Med
Author:
Liu JunORCID, Lahousse LiesORCID, Nivard Michel G.ORCID, Bot Mariska, Chen LianminORCID, van Klinken Jan Bert, Thesing Carisha S., Beekman MarianORCID, van den Akker Erik BenORCID, Slieker Roderick C.ORCID, Waterham Eveline, van der Kallen Carla J. H.ORCID, de Boer IreneORCID, Li-Gao Ruifang, Vojinovic Dina, Amin Najaf, Radjabzadeh Djawad, Kraaij Robert, Alferink Louise J. M., Murad Sarwa Darwish, Uitterlinden André G.ORCID, Willemsen Gonneke, Pool ReneORCID, Milaneschi Yuri, van Heemst Diana, Suchiman H. Eka D.ORCID, Rutters Femke, Elders Petra J. M., Beulens Joline W. J., van der Heijden Amber A. W. A., van Greevenbroek Marleen M. J., Arts Ilja C. W.ORCID, Onderwater Gerrit L. J., van den Maagdenberg Arn M. J. M., Mook-Kanamori Dennis O., Hankemeier Thomas, Terwindt Gisela M., Stehouwer Coen D. A., Geleijnse Johanna M.ORCID, ‘t Hart Leen M., Slagboom P. ElineORCID, van Dijk Ko WillemsORCID, Zhernakova Alexandra, Fu JingyuanORCID, Penninx Brenda W. J. H., Boomsma Dorret I., Demirkan Ayşe, Stricker Bruno H. C., van Duijn Cornelia M.ORCID
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference80 articles.
1. Patti, G. J., Yanes, O. & Siuzdak, G. Innovation: metabolomics: the apogee of the omics trilogy. Nat. Rev. Mol. Cell Biol. 13, 263–269 (2012). 2. Park, J. E., Lim, H. R., Kim, J. W. & Shin, K. H. Metabolite changes in risk of type 2 diabetes mellitus in cohort studies: a systematic review and meta-analysis. Diabetes Res. Clin. Pract. 140, 216–227 (2018). 3. McGarrah, R. W., Crown, S. B., Zhang, G. F., Shah, S. H. & Newgard, C. B. Cardiovascular metabolomics. Circ. Res. 122, 1238–1258 (2018). 4. Liu, J. et al. A Mendelian randomization study of metabolite profiles, fasting glucose, and type 2 diabetes. Diabetes 66, 2915–2926 (2017). 5. Wang, T. J. et al. Metabolite profiles and the risk of developing diabetes. Nat. Med. 17, 448–453 (2011).
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