Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/s41591-018-0034-6.pdf
Reference59 articles.
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4. Kotake, Y. et al. pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16 INK4α tumor suppressor gene. Genes Dev. 21, 49–54 (2007).
5. Mazur, P. K. et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature 510, 283–287 (2014).
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