Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells-Reference-Cited by-同舟云学术

Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells

Published:2016-11 Issue:11 Volume:6 Page:e492-e492
ISSN:2044-5385
Container-title:Blood Cancer Journal
language:en
Short-container-title:Blood Cancer Journal

Author:

Paulus A,Akhtar S,Caulfield T R,Samuel K,Yousaf H,Bashir Y,Paulus S M,Tran D,Hudec R,Cogen D,Jiang J,Edenfield B,Novak A,Ansell S M,Witzig T,Martin P,Coleman M,Roy V,Ailawadhi S,Chitta K,Linder S,Chanan-Khan A

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Hematology

Link

http://www.nature.com/articles/bcj201693.pdf

Reference54 articles.

1. Treon SP, Tripsas CK, Meid K, Warren D, Varma G, Green R et al. Ibrutinib in previously treated Waldenstrom's macroglobulinemia. N Engl J Med 2015; 372: 1430–1440.

2. Cao Y, Hunter ZR, Liu X, Xu L, Yang G, Chen J et al. The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's macroglobulinemia. Leukemia 2015; 29: 169–176.

3. Young RM, Staudt LM . Ibrutinib treatment of CLL: the cancer fights back. Cancer Cell 2014; 26: 11–13.

4. Woyach JA, Furman RR, Liu TM, Ozer HG, Zapatka M, Ruppert AS et al. Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib. N Engl J Med 2014; 370: 2286–2294.

5. Furman RR, Cheng S, Lu P, Setty M, Perez AR, Guo A et al. Ibrutinib resistance in chronic lymphocytic leukemia. N Engl J Med 2014; 370: 2352–2354.

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