Ochratoxin A induced early hepatotoxicity: new mechanistic insights from microRNA, mRNA and proteomic profiling studies

Author:

Qi Xiaozhe,Yang Xuan,Chen Siyuan,He Xiaoyun,Dweep Harsh,Guo Mingzhang,Cheng Wen-Hsing,Xu Wentao,Luo Yunbo,Gretz Norbert,Dai Qiu,Huang Kunlun

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference50 articles.

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2. Aydin, G., Ozcelik, N., Cicek, E. & Soyoz, M. Histopathologic changes in liver and renal tissues induced by Ochratoxin A and melatonin in rats. Hum Exp Toxicol. 22, 383–391 (2003).

3. Ferrante, M. C. et al. Expression of COX-2 and hsp72 in peritoneal macrophages after an acute ochratoxin A treatment in mice. Life Sci. 79, 1242–1247 (2006).

4. Palabiyik, S. S. et al. ochratoxin A causes oxidative stress and cell death in rat liver. World mycotoxin J. 5, 377–384 (2012).

5. Rached, E. et al. Ochratoxin A: 13-week oral toxicity and cell proliferation in male F344/n rats. Toxicol Sci. 97, 288–298 (2007).

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