Aldosterone antagonists are underused by clinicians
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cardiology and Cardiovascular Medicine
Link
http://www.nature.com/articles/nrcardio.2009.244.pdf
Reference10 articles.
1. Pitt, B. et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N. Engl. J. Med. 341, 709–717 (1999).
2. Pitt, B. et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N. Engl. J. Med. 348, 1309–1321 (2003).
3. Albert, N. M. et al. Use of aldosterone antagonists in heart failure. JAMA 302, 1658–1665 (2009).
4. Tait, S. A., Tait, J. F. & Coghlan, J. P. The discovery, isolation and identification of aldosterone: reflections on emerging regulation and function. Mol. Cell. Endocrinol. 217, 1–21 (2004).
5. Menard, J. The 45-year story of the development of an anti-aldosterone more specific than spironolactone. Mol. Cell. Endocrinol. 217, 45–52 (2004).
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