Motors and switches: AAA+ machines within the replisome
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm949.pdf
Reference100 articles.
1. Stukenberg, P. T., Studwell-Vaughan, P. S. & O'Donnell, M. Mechanism of the sliding β-clamp of DNA polymerase III holoenzyme. J. Biol. Chem. 266, 11328–11334 (1991).Reveals that β binds DNA topologically, and indicates that it encircles DNA like a doughnut.
2. Kong, X. P., Onrust, R., O'Donnell, M. & Kuriyan, J. Three-dimensional structure of the β-subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp. Cell 69, 425–437 (1992).The crystal structure of the β-sliding clamp confirmed the biochemical prediction of a ring shape for the β-dimer. It also revealed the unexpected three-domain architecture of β, giving the dimer a sixfold appearance.
3. Baker, T. A. & Bell, S. P. Polymerases and the replisome: machines within machines. Cell 92, 295–305 (1998).
4. Davey, M. J. & O'Donnell, M. Mechanisms of DNA replication. Curr. Opin. Chem. Biol. 4, 581–586 (2000).
5. Jeruzalmi, D., O'Donnell, M. & Kuriyan, J. Clamp loaders and sliding clamps. Curr. Opin. Struct. Biol. 12, 217–224 (2002).
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