1. Sheiner, L. B. Learning versus confirming in clinical drug development. Clin. Pharmacol. Ther. 61, 275–291 (1997).
2. Levy, G. in Pharmacodynamics and Toxicokinetics in Rational Drug Development (Plenum, New York, 1993).
3. Booz Allen Hamilton & Credit Suisse First Boston. Know thy R&D enemy: the key to fighting attrition. IN VIVO 19, 59 (2005).
4. Meyer, J. M. & Ginsburg, G. S. The path to personalized medicine. Curr. Opin. Chem. Biol. 6, 434–438 (2002).
5. Pharma 2010: The Threshold on Innovation. IBM Business Consulting Services [online], <
http://www-1.ibm.com/services/us/index.wss/xs/imc/a1001099
> (April 2004).