Power tools for gene expression and clonal analysis in Drosophila-Reference-Cited by-同舟云学术

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Power tools for gene expression and clonal analysis in Drosophila

Published:2011-12-28 Issue:1 Volume:9 Page:47-55
ISSN:1548-7091
Container-title:Nature Methods
language:en
Short-container-title:Nat Methods

Author:

del Valle Rodríguez Alberto,Didiano Dominic,Desplan Claude

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Biochemistry,Biotechnology

Link

http://www.nature.com/articles/nmeth.1800.pdf

Reference64 articles.

1. Brand, A.H. & Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401–415 (1993).

2. Luan, H., Peabody, N.C., Vinson, C.R. & White, B.H. Refined spatial manipulation of neuronal function by combinatorial restriction of transgene expression. Neuron 52, 425–436 (2006).

3. Potter, C.J., Tasic, B., Russler, E.V., Liang, L. & Luo, L. The Q system: a repressible binary system for transgene expression, lineage tracing, and mosaic analysis. Cell 141, 536–548 (2010).

4. Lee, T. & Luo, L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22, 451–461 (1999). In this important paper for cell-lineage studies, the MARCM technique was described, which allows for the generation of labeled mutant cells in otherwise wild-type organisms.

5. Griffin, R. et al. The twin spot generator for differential Drosophila lineage analysis. Nat. Methods 6, 600–602 (2009). Together with reference 6, this paper describes a system for the fruit fly that allows labeling the two progeny of a cell in two different colors, facilitating cell-lineage and gene-function studies.

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