CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis-Reference-Cited by-同舟云学术

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis

Published:2016-10-14 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Naert Thomas,Colpaert Robin,Van Nieuwenhuysen Tom,Dimitrakopoulou Dionysia,Leoen Jannick,Haustraete Jurgen,Boel Annekatrien,Steyaert Wouter,Lepez Trees,Deforce Dieter,Willaert Andy,Creytens David,Vleminckx Kris

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep35264.pdf

Reference41 articles.

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3. Knudson, A. G., Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68, 820–823 (1971).

4. Friend, S. H. et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323, 643–646, doi: 10.1038/323643a0 (1986).

5. Stratton, M. R. et al. Structural alterations of the RB1 gene in human soft tissue tumours. Br J Cancer 60, 202–205 (1989).

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