Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Immunology
Link
http://www.nature.com/articles/gene201457.pdf
Reference52 articles.
1. Harley JB, Kelly JA, Kaufman KM . Unraveling the genetics of systemic lupus erythematosus. Springer Semin Immunopathol 2006; 28: 119–130.
2. Ko K, Koldobskaya Y, Rosenzweig E, Niewold TB . Activation of the interferon pathway is dependent upon autoantibodies in African-American SLE patients, but not in European-American SLE patients. Front Immunol 2013; 4: 309.
3. Sanchez E, Comeau ME, Freedman BI, Kelly JA, Kaufman KM, Langefeld CD et al. Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study. Arthritis Rheum 2011; 63: 3493–3501.
4. Ko K, Franek BS, Marion M, Kaufman KM, Langefeld CD, Harley JB et al. Genetic ancestry, serum interferon-alpha activity, and autoantibodies in systemic lupus erythematosus. J Rheumatol 2012; 39: 1238–1240.
5. Niewold TB, Hua J, Lehman TJ, Harley JB, Crow MK . High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun 2007; 8: 492–502.
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