Mitigating risk in academic preclinical drug discovery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd4578.pdf
Reference102 articles.
1. Frye, S., Crosby, M., Edwards, T. & Juliano, R. US academic drug discovery. Nature Rev. Drug Discov. 10, 409–410 (2011). This is a comprehensive overview of the state and challenges of US academic drug discovery pre-2011.
2. Abou-Gharbia, M. & Childers, W. E. Discovery of innovative therapeutics: today's realities and tomorrow's vision. 2. Pharma's challenges and their commitment to innovation. J. Med. Chem. 57, 5525–5553 (2014).
3. Khanna, I. Drug discovery in pharmaceutical industry: productivity challenges and trends. Drug Discov. Today 17, 1088–1102 (2012).
4. Zoghbi, H. Y. The basics of translation. Science 339, 250 (2013).
5. Gurvich, V. J. & Byrn, S. R. NIPTE: a multi-university partnership supporting academic drug development. Drug Discov. Today 18, 916–921 (2013).
Cited by 143 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. GETdb: A comprehensive database for genetic and evolutionary features of drug targets;Computational and Structural Biotechnology Journal;2024-12
2. The Accurate Prediction of Antibody Deamidations by Combining High-Throughput Automated Peptide Mapping and Protein Language Model-Based Deep Learning;Antibodies;2024-09-10
3. The Role of Artificial Intelligence in Revolutionizing Pharmacological Research;Current Pharmacology Reports;2024-09-03
4. Assessment of sedative activity of fraxin: In vivo approach along with receptor binding affinity and molecular interaction with GABAergic system;Drug Development Research;2024-08-17
5. Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL);Pharmaceuticals;2024-08-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3