Monooxygenation of rifampicin catalyzed by the rox gene product of Nocardia farcinica: structure elucidation, gene identification and role in drug resistance-Reference-Cited by-同舟云学术

Monooxygenation of rifampicin catalyzed by the rox gene product of Nocardia farcinica: structure elucidation, gene identification and role in drug resistance

Published:2009-11-27 Issue:1 Volume:63 Page:23-28
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Hoshino Yasutaka,Fujii Shoko,Shinonaga Hideki,Arai Koshi,Saito Fumiko,Fukai Toshio,Satoh Hiroyuki,Miyazaki Yoshitsugu,Ishikawa Jun

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja2009116.pdf

Reference14 articles.

1. Ishikawa, J. et al. The complete genomic sequence of Nocardia farcinica IFM 10152. Proc. Natl Acad. Sci. USA 101, 14925–14930 (2004).

2. Ishikawa, J., Chiba, K., Kurita, H. & Satoh, H. Contribution of rpoB2 RNA polymerase β subunit gene to rifampin resistance in Nocardia species. Antimicrob. Agents Chemother. 50, 1342–1346 (2006).

3. Tanaka, Y. et al. Different rifampicin inactivation mechanisms in Nocardia and related taxa. Microbiol. Immunol. 40, 1–4 (1996).

4. Yazawa, K. et al. Inactivation of rifampin by Nocardia brasiliensis. Antimicrob. Agents Chemother. 37, 1313–1317 (1993).

5. Yazawa, K., Mikami, Y., Maeda, A., Morisaki, N. & Iwasaki, S. Phosphorylative inactivation of rifampicin by Nocardia otitidiscaviarum. J. Antimicrob. Chemother. 33, 1127–1135 (1994).

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