Enantioselective total synthesis of atpenin A5-Reference-Cited by-同舟云学术

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Enantioselective total synthesis of atpenin A5

Published:2009-04-17 Issue:6 Volume:62 Page:289-294
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Ohtawa Masaki,Ogihara Satoru,Sugiyama Kouhei,Shiomi Kazuro,Harigaya Yoshihiro,Nagamitsu Tohru,Ōmura Satoshi

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja200929.pdf

Reference13 articles.

1. Ōmura, S. et al. Atpenins, new antifungal antibiotics produced by Penicillium sp. Production, isolation, physico-chemical and biological properties. J. Antibiot. 41, 1769–1773 (1988).

2. Oshino, K., Kumagai, H., Tomoda, H. & Ōmura, S. Mechanism of action of atpenin B on Raji cells. J. Antibiot. 43, 1064–1068 (1990).

3. Kumagai, H. et al. The structures of atpenins A4, A5 and B, new antifungal antibiotics produced by Penicillium sp. J. Antibiot. 43, 1553–1558 (1990).

4. Trécourt, F., Mallet, M., Mongin, O. & Quéguiner, G. Total synthesis of (±)-Atpenin B. An original ‘Clockwise’ functionalization of 2-chloropyridine. J. Org. Chem. 59, 6173–6178 (1994).

5. Miyadera, H. et al. Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase). Proc. Natl Acad. Sci. USA 100, 473–477 (2003).

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