The first examples of chemical modification of oligomycin A

Author:

Lysenkova Lyudmila N,Turchin Konstantin F,Danilenko Valery N,Korolev Alexander M,Preobrazhenskaya Maria N

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Reference21 articles.

1. Wender, P. A. et al. Correlation of F0F1-ATPase inhibition and antiproliferative activity of apoptolidin analogues. Org. Lett. 8, 589–592 (2006).

2. Smith, R. M., Peterson, W. H. & McCoy, E. Oligomycin, a new antifungal antibiotic. Antibiot. Chemother. 4, 962 (1954).

3. Salomon, A. R., Voehringer, D. W., Herzenberg, L. A. & Khosla, C. Understanding and exploiting the mechanistic basis for selectivity of polyketide inhibitors of F0F1-ATPase. Proc. Natl Acad. Sci. USA 97, 14766–14771 (2000).

4. Alekseeva, M. G., Elizarov, S. M., Bekker, O. B., Lubimova, I. K. & Danilenko, V. N. F0F1ATP synthase of streptomycetes: modulation of activity and oligomycin resistance by protein Ser/Thr kinases. Biologicheskie Membrany (Rus) 26, 41–49 (2009).

5. Kim, B. S., Surk Sik Moon, S. S. & Hwang, B. K. Isolation, identification, and antifungal activity of a macrolide antibiotic, oligomycin A, produced by Streptomyces libani. Can. J. Bot. 77, 850–858 (1999).

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