Dinapinones, novel inhibitors of triacylglycerol synthesis in mammalian cells, produced by Penicillium pinophilum FKI-3864-Reference-Cited by-同舟云学术

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Dinapinones, novel inhibitors of triacylglycerol synthesis in mammalian cells, produced by Penicillium pinophilum FKI-3864

Published:2011-05-11 Issue:7 Volume:64 Page:489-494
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Ohte Satoshi,Matsuda Daisuke,Uchida Ryuji,Nonaka Kenichi,Masuma Rokuro,Ōmura Satoshi,Tomoda Hiroshi

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja201132.pdf

Reference25 articles.

1. Bray, G. A. et al. A double-blind randomized placebo-controlled trial of sibutramine. Obes. Res. 4, 263–270 (1996).

2. Rinaldi, C. M. et al. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett. 350, 240–244 (1994).

3. Davidson, M. H. et al. Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial. J. American. Med. Assoc. 281, 235–242 (1999).

4. Kopelman, P. et al. Cetilistat (ATL-962), a novel lipase inhibitor: a 12-week randomized, placebo-controlled study of weight reduction in obese patients. Internatl. J. Obes. 31, 494–499 (2007).

5. Smith, S. J. et al. Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat. Nat. Genet. 25, 87–90 (2000).

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