Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase

Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis

Published:2017-02-13 Issue:3 Volume:23 Page:291-300
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Chuang Chen-Hua,Greenside Peyton G,Rogers Zoë N,Brady Jennifer J,Yang Dian,Ma Rosanna K,Caswell Deborah R,Chiou Shin-Heng,Winters Aidan F,Grüner Barbara M,Ramaswami Gokul,Spencley Andrew L,Kopecky Kimberly E,Sayles Leanne C,Sweet-Cordero E Alejandro,Li Jin Billy^ORCID,Kundaje Anshul,Winslow Monte M

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.4285.pdf

Reference73 articles.

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3. Winslow, M.M. et al. Suppression of lung adenocarcinoma progression by Nkx2-1. Nature 473, 101–104 (2011).

4. Bos, P.D. et al. Genes that mediate breast cancer metastasis to the brain. Nature 459, 1005–1009 (2009).

5. Nguyen, D.X. et al. WNT–TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell 138, 51–62 (2009).

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