Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Structural Biology
Link
http://www.nature.com/articles/nsmb.1976.pdf
Reference37 articles.
1. Gettins, P.G. Serpin structure, mechanism, and function. Chem. Rev. 102, 4751–4804 (2002).
2. Huntington, J.A., Read, R.J. & Carrell, R.W. Structure of a serpin-protease complex shows inhibition by deformation. Nature 407, 923–926 (2000).
3. Dupont, D.M. et al. Biochemical properties of plasminogen activator inhibitor-1. Front. Biosci. 14, 1337–1361 (2009).
4. Mushunje, A., Evans, G., Brennan, S.O., Carrell, R.W. & Zhou, A. Latent antithrombin and its detection, formation and turnover in the circulation. J. Thromb. Haemost. 2, 2170–2177 (2004).
5. Kaslik, G. et al. Effects of serpin binding on the target proteinase: global stabilization, localized increased structural flexibility, and conserved hydrogen bonding at the active site. Biochemistry 36, 5455–5464 (1997).
Cited by 50 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. ER chaperones use a protein folding and quality control glyco-code;Molecular Cell;2023-12
2. In‐situ PLL‐g‐PEG Functionalized Nanopore for Enhancing Protein Characterization;Chemistry – An Asian Journal;2023-07-27
3. The conformational landscape of a serpin N-terminal subdomain facilitates folding and in-cell quality control;2023-04-26
4. Impact of the PEG length and PEGylation site on the structural, thermodynamic, thermal, and proteolytic stability of mono‐PEGylated alpha‐1 antitrypsin;Protein Science;2022-08-13
5. Furin-cleavage site is present in an antiparallel β-strand in SARS-CoV2 Spike protein;2022-02-18
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3