PKPD Modeling of Predictors for Adverse Effects and Overall Survival in Sunitinib-Treated Patients With GIST
Author:
Affiliation:
1. Department of Pharmaceutical Biosciences; Uppsala University; Uppsala Sweden
2. Pfizer Global Research and Development, New York; New York USA
3. Metrum Research Group; Tariffville Connecticut USA
Publisher
Wiley
Subject
Pharmacology (medical),Modelling and Simulation
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1038/psp.2013.62/fullpdf
Reference28 articles.
1. Moving towards dose individualization of tyrosine kinase inhibitors;Klümpen;Cancer Treat. Rev.,2011
2. Hansson , E.K. et al PKPD modeling of VEGF, sVEGFR-2, -3 and sKIT as predictors of tumor dynamics and overall survival following sunitinib treatment in GIST CPT Pharmacometrics Syst. Pharmacol. 2013
3. Model-based prediction of phase III overall survival in colorectal cancer on the basis of phase II tumor dynamics;Claret;J. Clin. Oncol.,2009
4. The clinical toxicity profile of vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) targeting angiogenesis inhibitors; a review;Eskens;Eur. J. Cancer,2006
5. Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib;Rini;J. Natl. Cancer Inst.,2011
Cited by 41 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. A Pharmacodynamic Study of Aminoglycosides against Pathogenic E. coli through Monte Carlo Simulation;Pharmaceuticals;2023-12-24
2. Assessment of ibrutinib scheduling on leukocyte, lymph node size and blood pressure dynamics in chronic lymphocytic leukemia through pharmacokinetic‐pharmacodynamic models;CPT: Pharmacometrics & Systems Pharmacology;2023-07-26
3. Pharmacokinetic–Pharmacodynamic Modeling and Simulation in Clinical Practice and Studies;AAPS Introductions in the Pharmaceutical Sciences;2023
4. Optimization of blood pressure measurement practices for pharmacodynamic analyses of tyrosine‐kinase inhibitors;Clinical and Translational Science;2022-10-18
5. Early response dynamics predict treatment failure in patients with recurrent and/or metastatic head and neck squamous cell carcinoma treated with cetuximab and nivolumab;Oral Oncology;2022-04
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3