Effect of CYP3A4*22, CYP3A5*3, and CYP3A Combined Genotypes on Cyclosporine, Everolimus, and Tacrolimus Pharmacokinetics in Renal Transplantation-Reference-Cited by-同舟云学术

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Effect of CYP3A4*22, CYP3A5*3, and CYP3A Combined Genotypes on Cyclosporine, Everolimus, and Tacrolimus Pharmacokinetics in Renal Transplantation

Published:2014-02 Issue:2 Volume:3 Page:100
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT: Pharmacometrics & Systems Pharmacology

Author:

Moes DJAR¹²,Swen JJ¹²,den Hartigh J¹,van der Straaten T¹,van der Heide JJ Homan³,Sanders JS⁴,Bemelman FJ³,de Fijter JW²,Guchelaar HJ¹

Affiliation:

1. Department of Clinical Pharmacy and Toxicology; Leiden University Medical Center; Leiden The Netherlands

2. Department of Nephrology; Leiden University Medical Center; Leiden The Netherlands

3. Department of Nephrology; Academic Medical Center; Amsterdam The Netherlands

4. Department of Nephrology; University Medical Center Groningen; Groningen The Netherlands

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1038/psp.2013.78/fullpdf

Reference50 articles.

1. CYP3A5 and CYP3A4 but not MDR1 single-nucleotide polymorphisms determine long-term tacrolimus disposition and drug-related nephrotoxicity in renal recipients;Kuypers;Clin. Pharmacol. Ther.,2007

2. Longitudinal assessment of everolimus in de novo renal transplant recipients over the first post-transplant year: pharmacokinetics, exposure-response relationships, and influence on cyclosporine;Kovarik;Clin. Pharmacol. Ther.,2001

3. Pharmacokinetics and clinical tolerance of intravenous and oral cyclosporine in the immediate postoperative period;Morse;Clin. Pharmacol. Ther.,1988

4. Clinical pharmacokinetics of everolimus;Kirchner;Clin. Pharmacokinet.,2004

5. Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD;Jacobsen;Transplant. Proc.,2001

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