Metformin treatment reduces motor and neuropsychiatric phenotypes in the zQ175 mouse model of Huntington disease-Reference-Cited by-同舟云学术

Metformin treatment reduces motor and neuropsychiatric phenotypes in the zQ175 mouse model of Huntington disease

Published:2019-06 Issue:6 Volume:51 Page:1-16
ISSN:1226-3613
Container-title:Experimental & Molecular Medicine
language:en
Short-container-title:Exp Mol Med

Author:

Sanchis Ana,García-Gimeno María Adelaida,Cañada-Martínez Antonio José^ORCID,Sequedo María Dolores,Millán José María,Sanz Pascual,Vázquez-Manrique Rafael P.^ORCID

Funder

Generalitat Valenciana

Publisher

Springer Science and Business Media LLC

Subject

Clinical Biochemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://www.nature.com/articles/s12276-019-0264-9.pdf

Reference62 articles.

1. Krobitsch, S. & Kazantsev, A. G. Huntington's disease: from molecular basis to therapeutic advances. Int. J. Biochem. Cell Biol. 43, 20–24 (2011).

2. Ferrante, R. J., Kowall, N. W. & Richardson, E. P. Jr Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry. J. Neurosci. 11, 3877–3887 (1991).

3. Yamamoto, A., Cremona, M. L. & Rothman, J. E. Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway. J. Cell Biol. 172, 719–731 (2006).

4. Ortega, Z. & Lucas, J. J. Ubiquitin-proteasome system involvement in Huntington’s disease. Front. Mol. Neurosci. 7, 77 (2014).

5. Herrero-Martin, G. et al. TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells. EMBO J. 28, 677–685 (2009).

Cited by 53 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Antidiabetic Drug Metformin Attenuated Depressive and Anxiety-like Behaviors and Oxidative Stress in the Brain in a Rodent Model of Inflammation Induced by Lipopolysaccharide in Male Rats;Endocrine, Metabolic & Immune Disorders - Drug Targets;2024-10

2. Advances in Clinical Therapies for Huntington's Disease and the Promise of Multi‐Targeted/Functional Drugs Based on Clinicaltrials.gov;Clinical Pharmacology & Therapeutics;2024-06-11

3. Beneficial effects of metformin treatment on memory impairment;Molecular Biology Reports;2024-05-10

4. Indole-Based Compounds in the Development of Anti-Neurodegenerative Agents;Molecules;2024-05-03

5. Polyglutamine disorders: Pathogenesis and potential drug interventions;Life Sciences;2024-05