Quantifying the stabilizing effects of protein–ligand interactions in the gas phase
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry
Link
http://www.nature.com/articles/ncomms9551.pdf
Reference41 articles.
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3. Niu, S., Rabuck, J. N. & Ruotolo, B. T. Ion mobility-mass spectrometry of intact protein–ligand complexes for pharmaceutical drug discovery and development. Curr. Opin. Chem. Biol. 17, 809–817 (2013) .
4. Benesch, J. L. P. Collisional activation of protein complexes: picking up the pieces. J. Am. Soc. Mass. Spectrom. 20, 341–348 (2009) .
5. Ruotolo, B. T. et al. Ion mobility-mass spectrometry reveals long-lived, unfolded intermediates in the dissociation of protein complexes. Angew. Chem. Int. Ed. Engl. 46, 8001–8004 (2007) .
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