The β-globin Replicator greatly enhances the potential of S/MAR based episomal vectors for gene transfer into human haematopoietic progenitor cells-Reference-Cited by-同舟云学术

The β-globin Replicator greatly enhances the potential of S/MAR based episomal vectors for gene transfer into human haematopoietic progenitor cells

Published:2017-01-20 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Stavrou Eleana F.,Lazaris Vassileios M.,Giannakopoulos Aristeidis,Papapetrou Eirini,Spyridonidis Alexandros,Zoumbos Nikolas C.,Gkountis Antonis,Athanassiadou Aglaia

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep40673.pdf

Reference41 articles.

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2. Piechaczek, C., Fetzer, C., Baiker, A., Bode, J. & Lipps, H. J. A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells. Nucleic acids research 27, 426–428 (1999).

3. Marie, C. et al. pFARs, plasmids free of antibiotic resistance markers, display high-level transgene expression in muscle, skin and tumour cells. The journal of gene medicine 12, 323–332, doi: 10.1002/jgm.1441 (2010).

4. Gracey Maniar, L. E. et al. Minicircle DNA vectors achieve sustained expression reflected by active chromatin and transcriptional level. Molecular therapy: the journal of the American Society of Gene Therapy 21, 131–138, doi: 10.1038/mt.2012.244 (2013).

5. Verghese, S. C., Goloviznina, N. A., Skinner, A. M., Lipps, H. J. & Kurre, P. S/MAR sequence confers long-term mitotic stability on non-integrating lentiviral vector episomes without selection. Nucleic Acids Res 42, e53, doi: 10.1093/nar/gku082 (2014).

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