A new unexpected twist in newborn immunity
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
http://www.nature.com/articles/nm.3448.pdf
Reference10 articles.
1. Elahi, S. et al. Immunosuppressive CD71 erythroid cells compromise neonatal host defence against infection. Nature 504, 158–162 (2013).
2. Adkins, B. Neonatal immunology: responses to pathogenic microorganisms and epigenetics reveal an “immunodiverse” developmental state. Immunol. Res. 57, 246–257 (2013).
3. Levy, O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat. Rev. Immunol. 7, 379–390 (2007).
4. Mold, J.E. et al. Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. Science 330, 1695–1699 (2010).
5. Pettengill, M. et al. Soluble ecto-5′-nucleotidase (5′NT), alkaline phosphatase, and adenosine deaminase (ADA1) activities in neonatal blood favor elevated extracellular adenosine. J. Biol. Chem. 288, 27315–27326 (2013).
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2. Age predicts cytokine kinetics and innate immune cell activation following intranasal delivery of IFNγ and GM-CSF in a mouse model of RSV infection;Cytokine;2017-09
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