Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress-Reference-Cited by-同舟云学术

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Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress

Published:2010-11-12 Issue:2 Volume:25 Page:236-245
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Blalock W L,Bavelloni A,Piazzi M,Tagliavini F,Faenza I,Martelli A M,Follo M Y,Cocco L

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/leu2010264.pdf

Reference38 articles.

1. Roberts WK, Clemens MJ, Kerr IM . Interferon-induced inhibition of protein synthesis in L-cell extracts: an ATP-dependent step in the activation of an inhibitor by double-stranded RNA. Proc Natl Acad Sci USA 1976; 73: 3136–3140.

2. Williams BR . PKR; a sentinel kinase for cellular stress. Oncogene 1999; 18: 6112–6120.

3. Sadler AJ, Latchoumanin O, Hawkes D, Mak J, Williams BR . An antiviral response directed by PKR phosphorylation of the RNA helicase A. PLoS Pathog 2009; 5: e1000311.

4. Blalock WL, Bavelloni A, Piazzi M, Faenza I, Cocco L . A role for PKR in hematologic malignancies. J Cell Physiol 2010; 223: 572–591.

5. Yoon CH, Miah MA, Kim KP, Bae YS . New Cdc2 Tyr 4 phosphorylation by dsRNA-activated protein kinase triggers Cdc2 polyubiquitination and G2 arrest under genotoxic stresses. EMBO Rep 2010; 11: 393–399.

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