The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures-Reference-Cited by-同舟云学术

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The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures

Published:2010-10-29 Issue:1 Volume:25 Page:135-144
ISSN:0887-6924
Container-title:Leukemia
language:en
Short-container-title:Leukemia

Author:

Benedikt A,Baltruschat S,Scholz B,Bursen A,Arrey T N,Meyer B,Varagnolo L,Müller A M,Karas M,Dingermann T,Marschalek R

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Cancer Research,Hematology

Link

http://www.nature.com/articles/leu2010249.pdf

Reference44 articles.

1. Meyer C, Kowarz E, Hofmann J, Renneville A, Zuna J, Trka J et al. New Insights into the MLL recombinome of acute leukemias. Leukemia 2009; 23: 1490–1499.

2. Nilson I, Reichel M, Ennas MG, Greim R, Knörr C, Siegler G et al. Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia. Br J Haematol 1997; 98: 157–169.

3. Chen W, Li Q, Hudson WA, Kumar A, Kirchhof N, Kersey JH . A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy. Blood 2006; 108: 669–677.

4. Metzler M, Forster A, Pannell R, Arends MJ, Daser A, Lobato MN et al. A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology. Oncogene 2006; 25: 3093–3103.

5. Krivtsov AV, Feng Z, Lemieux ME, Faber J, Vempati S, Sinha AU et al. H3K79 methylation profiles define murine and human MLL-AF4 leukemias. Cancer Cell 2008; 14: 355–368.

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