Regulatory T cells in nonlymphoid tissues
Author:
Publisher
Springer Science and Business Media LLC
Subject
Immunology,Immunology and Allergy
Link
http://www.nature.com/articles/ni.2683.pdf
Reference81 articles.
1. Josefowicz, S.Z., Lu, L.F., Rudensky, A.Y. & Regulatory, T. Cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 30, 531–564 (2012).
2. Feuerer, M., Hill, J.A., Mathis, D. & Benoist, C. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat. Immunol. 10, 689–695 (2009).
3. Zheng, Y. et al. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature 458, 351–356 (2009).
4. Koch, M.A. et al. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat. Immunol. 10, 595–602 (2009).In references 3 and 4, the concept is introduced that T reg cells adapt their phenotype to match the type of immune response they are controlling, sometimes sharing key segments of the transcriptional program with co-residing T effector cells.
5. Chaudhry, A. et al. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. Science 326, 986–991 (2009).
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