Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes-Reference-Cited by-同舟云学术

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Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

Published:2010-02-28 Issue:4 Volume:11 Page:350-354
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Mohan James F,Levisetti Matteo G,Calderon Boris,Herzog Jeremy W,Petzold Shirley J,Unanue Emil R

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.1850.pdf

Reference36 articles.

1. Anderson, M.S. & Bluestone, J.A. The NOD mouse: a model of immune disregulation. Annu. Rev. Immunol. 23, 447–485 (2005).

2. Zhang, L., Nakayama, M. & Eisenbarth, G.S. Insulin as an autoantigen in NOD/human diabetes. Curr. Opin. Immunol. 20, 111–118 (2008).

3. Wegmann, D.R., Norbury-Glaser, M. & Daniel, D. Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice. Eur. J. Immunol. 24, 1853–1857 (1994).

4. Wegmann, D.R., Gill, R.G., Norbury-Glaser, M., Schloot, N. & Daniel, D. Analysis of the spontaneous T cell response to insulin in NOD mice. J. Autoimmun. 7, 833–843 (1994).

5. Daniel, D., Gill, R.G., Schloot, N. & Wegmann, D. Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice. Eur. J. Immunol. 25, 1056–1062 (1995).

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